Emergence of new lineage of Dengue virus 3 (genotype III) in Lucknow, India
نویسندگان
چکیده
BACKGROUND AND OBJECTIVES Dengue has re-emerged as an important arboviral disease causing significant morbidity. It has become hyperendemic in the Indian subcontinent with all four known dengue serotypes circulating. MATERIALS AND METHODS Multiple sequence alignments and phylogenetic trees of DENV-3 were constructed to determine the extent of the isolated dengue virus genetic heterogeneity and phylogeny. RESULTS Sequencing and phylogenetic analysis of the C-prM gene junction revealed an active circulation of a new lineage of DENV-3 (genotype III) in this region of India. CONCLUSION Continuous epidemiological surveillance to monitor the incursion and spread of dengue virus genotypes in this region of India is needed.
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